Suryo Rahmanto, Aldwin
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma. [electronic resource]
- The EMBO journal 10 2016
- 2192-2212 p. digital
Publication Type: Journal Article
ISSN: 1460-2075
Standard No.: 10.15252/embj.201693889 doi
Subjects--Topical Terms: Aniline Compounds--pharmacology Animals Benzamides Cell Cycle Proteins--genetics Cell Line, Tumor Cell Movement Chromones--pharmacology Cisplatin--pharmacology F-Box Proteins--genetics F-Box-WD Repeat-Containing Protein 7 Glycogen Synthase Kinase 3--metabolism HEK293 Cells Humans Medulloblastoma--drug therapy Mice, Nude Morpholines--pharmacology Phosphatidylinositol 3-Kinases--metabolism Phosphoinositide-3 Kinase Inhibitors Protein Kinase Inhibitors--pharmacology Proto-Oncogene Proteins c-akt--antagonists & inhibitors Pyrimidines--pharmacology Pyrroles--pharmacology SOX9 Transcription Factor--genetics TOR Serine-Threonine Kinases--antagonists & inhibitors Ubiquitin-Protein Ligases--genetics Ubiquitination