TY - GEN AU - Mossine,Valeri V AU - Waters,James K AU - Chance,Deborah L AU - Mawhinney,Thomas P TI - Transient Proteotoxicity of Bacterial Virulence Factor Pyocyanin in Renal Tubular Epithelial Cells Induces ER-Related Vacuolation and Can Be Efficiently Modulated by Iron Chelators SN - 1096-0929 PY - 2018///0116 KW - Activating Transcription Factor 6 KW - genetics KW - Animals KW - Cell Line KW - Cell Proliferation KW - drug effects KW - Dose-Response Relationship, Drug KW - Endoplasmic Reticulum KW - Epithelial Cells KW - Glutathione KW - metabolism KW - Heat Shock Transcription Factors KW - Iron KW - Iron Chelating Agents KW - pharmacology KW - Kidney Tubules KW - NF-E2-Related Factor 2 KW - Necrosis KW - Oxidative Stress KW - Pseudomonas aeruginosa KW - Pyocyanine KW - chemical synthesis KW - Rats KW - Time Factors KW - Unfolded Protein Response KW - Vacuoles KW - Virulence N1 - Publication Type: Journal Article UR - https://doi.org/10.1093/toxsci/kfw174 ER -