TY - GEN AU - Mendes,Rui D AU - Canté-Barrett,Kirsten AU - Pieters,Rob AU - Meijerink,Jules P P TI - The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia SN - 1592-8721 PY - 2017///0707 KW - Amyloid Precursor Protein Secretases KW - antagonists & inhibitors KW - Animals KW - Antineoplastic Agents KW - therapeutic use KW - Drug Resistance, Neoplasm KW - genetics KW - Gene Expression Regulation, Leukemic KW - drug effects KW - Humans KW - Molecular Targeted Therapy KW - Mutation KW - PTEN Phosphohydrolase KW - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma KW - drug therapy KW - Proto-Oncogene Proteins c-akt KW - Receptor, Notch1 KW - Signal Transduction KW - Tumor Suppressor Proteins N1 - Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't UR - https://doi.org/10.3324/haematol.2016.146381 ER -