Mendes, Rui D <br/><br/>
The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia.  [electronic resource] 

 -  Haematologica  09 2016 
 - 1010-7 p.  digital 
<br/><br/> Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1592-8721 
<br/><br/><label>Standard No.: </label>10.3324/haematol.2016.146381  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amyloid Precursor Protein Secretases--antagonists & inhibitors<br/>Animals<br/>Antineoplastic Agents--therapeutic use<br/>Drug Resistance, Neoplasm--genetics<br/>Gene Expression Regulation, Leukemic--drug effects<br/>Humans<br/>Molecular Targeted Therapy<br/>Mutation<br/>PTEN Phosphohydrolase--genetics<br/>Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy<br/>Proto-Oncogene Proteins c-akt--genetics<br/>Receptor, Notch1--genetics<br/>Signal Transduction--drug effects<br/>Tumor Suppressor Proteins--genetics