TY - GEN AU - Bolduc,David M AU - Montagna,Daniel R AU - Seghers,Matthew C AU - Wolfe,Michael S AU - Selkoe,Dennis J TI - The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase SN - 2050-084X PY - 2017///1024 KW - Amyloid Precursor Protein Secretases KW - metabolism KW - Amyloid beta-Peptides KW - Amyloid beta-Protein Precursor KW - Catalytic Domain KW - Cells, Cultured KW - Humans KW - Immunoprecipitation KW - Kinetics KW - Mass Spectrometry KW - Protein Binding KW - Proteolysis N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.7554/eLife.17578 ER -