TY - GEN AU - Wu,Rentian AU - Nie,Qian AU - Tapper,Erin E AU - Jerde,Calvin R AU - Dunlap,Garrett S AU - Shrestha,Shikshya AU - Elraiyah,Tarig A AU - Offer,Steven M AU - Diasio,Robert B TI - Histone H3K27 Trimethylation Modulates 5-Fluorouracil Resistance by Inhibiting PU.1 Binding to the DPYD Promoter SN - 1538-7445 PY - 2017///0811 KW - Dihydrouracil Dehydrogenase (NADP) KW - genetics KW - Drug Resistance, Neoplasm KW - Enhancer of Zeste Homolog 2 Protein KW - physiology KW - Fluorouracil KW - pharmacology KW - Histones KW - metabolism KW - Humans KW - Methylation KW - Promoter Regions, Genetic KW - Proto-Oncogene Proteins KW - antagonists & inhibitors KW - Trans-Activators KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1158/0008-5472.CAN-16-1306 ER -