TY - GEN AU - Sasaki,Nobuo AU - Sachs,Norman AU - Wiebrands,Kay AU - Ellenbroek,Saskia I J AU - Fumagalli,Arianna AU - Lyubimova,Anna AU - Begthel,Harry AU - van den Born,Maaike AU - van Es,Johan H AU - Karthaus,Wouter R AU - Li,Vivian S W AU - López-Iglesias,Carmen AU - Peters,Peter J AU - van Rheenen,Jacco AU - van Oudenaarden,Alexander AU - Clevers,Hans TI - Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon SN - 1091-6490 PY - 2018///0125 KW - Animals KW - Colon KW - cytology KW - Colonic Neoplasms KW - metabolism KW - Epithelial Cells KW - Intestine, Small KW - Mice KW - Neoplasm Proteins KW - genetics KW - Organoids KW - growth & development KW - Pancreatitis-Associated Proteins KW - Paneth Cells KW - Receptors, G-Protein-Coupled KW - Receptors, Notch KW - Stem Cell Niche KW - Stem Cells KW - Wnt Signaling Pathway N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1607327113 ER -