TY  - GEN
AU  - Renata,Hans
AU  - Lewis,Russell D
AU  - Sweredoski,Michael J
AU  - Moradian,Annie
AU  - Hess,Sonja
AU  - Wang,Z Jane
AU  - Arnold,Frances H
TI  - Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes
SN  - 1520-5126
PY  - 2018///0523
KW  - Amino Acid Sequence
KW  - Catalysis
KW  - Coenzymes
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - chemistry
KW  - Escherichia coli
KW  - metabolism
KW  - Heme
KW  - Models, Molecular
KW  - Mutagenesis, Site-Directed
KW  - Protein Conformation
KW  - Protein Engineering
KW  - methods
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1021/jacs.6b06823
ER  -