TY - GEN AU - Gao,Xiaoxia AU - Xie,Cen AU - Wang,Yuanyuan AU - Luo,Yuhong AU - Yagai,Tomoki AU - Sun,Dongxue AU - Qin,Xuemei AU - Krausz,Kristopher W AU - Gonzalez,Frank J TI - The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4 SN - 1873-2968 PY - 2017///0509 KW - Animals KW - Bile Acids and Salts KW - metabolism KW - Cell Line, Tumor KW - Flutamide KW - chemistry KW - Gene Expression Regulation KW - drug effects KW - Hepatocytes KW - Homeostasis KW - Ligands KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Models, Molecular KW - Multidrug Resistance-Associated Proteins KW - genetics KW - Protein Binding KW - Protein Conformation KW - Receptors, Aryl Hydrocarbon N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bcp.2016.08.021 ER -