Gao, Xiaoxia

The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4. [electronic resource] - Biochemical pharmacology Nov 2016 - 93-104 p. digital

Publication Type: Journal Article

1873-2968

10.1016/j.bcp.2016.08.021 doi


Animals
Bile Acids and Salts--metabolism
Cell Line, Tumor
Flutamide--chemistry
Gene Expression Regulation--drug effects
Hepatocytes
Homeostasis--drug effects
Ligands
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Molecular
Multidrug Resistance-Associated Proteins--genetics
Protein Binding
Protein Conformation
Receptors, Aryl Hydrocarbon--metabolism