Masuda, Mari <br/><br/>
TNIK inhibition abrogates colorectal cancer stemness.  [electronic resource] 

 -  Nature communications  08 2016 
 - 12586 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2041-1723 
<br/><br/><label>Standard No.: </label>10.1038/ncomms12586  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenomatous Polyposis Coli Protein--genetics<br/>Administration, Oral<br/>Aged<br/>Animals<br/>Azoxymethane--toxicity<br/>Carcinogenesis--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Transformation, Neoplastic--pathology<br/>Colorectal Neoplasms--chemically induced<br/>Crystallography, X-Ray<br/>Female<br/>Germinal Center Kinases<br/>Humans<br/>Imidazoles--pharmacology<br/>Male<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Mice, Nude<br/>Middle Aged<br/>Mutation<br/>Neoplastic Stem Cells--drug effects<br/>Protein Binding<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Quinazolines--pharmacology<br/>Recombinant Proteins--genetics<br/>Ubiquitin-Protein Ligases<br/>Wnt Proteins--metabolism<br/>Wnt Signaling Pathway--drug effects<br/>Xenograft Model Antitumor Assays<br/>beta Catenin--genetics