Guerra, Borja <br/><br/>
CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia.  [electronic resource] 

 -  Oncotarget  05 2017 
 - 29679-29698 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1949-2553 
<br/><br/><label>Standard No.: </label>10.18632/oncotarget.11425  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Cell Cycle--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Disease Models, Animal<br/>Drug Resistance, Neoplasm--drug effects<br/>Female<br/>Fusion Proteins, bcr-abl--genetics<br/>Humans<br/>Imatinib Mesylate--pharmacology<br/>JNK Mitogen-Activated Protein Kinases--metabolism<br/>K562 Cells<br/>Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy<br/>Mice<br/>Naphthoquinones--pharmacology<br/>Protein Kinase Inhibitors--pharmacology<br/>STAT5 Transcription Factor--metabolism<br/>Signal Transduction<br/>Xenograft Model Antitumor Assays