TY  - GEN
AU  - Kelly,Kevin
AU  - Mejia,Alex
AU  - Suhasini,Avvaru N
AU  - Lin,An-Ping
AU  - Kuhn,John
AU  - Karnad,Anand B
AU  - Weitman,Steven
AU  - Aguiar,Ricardo C T
TI  - Safety and Pharmacodynamics of the PDE4 Inhibitor Roflumilast in Advanced B-cell Malignancies
SN  - 1557-3265
PY  - 2018///0209
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Aminopyridines
KW  - administration & dosage
KW  - B-Lymphocytes
KW  - drug effects
KW  - Benzamides
KW  - Cyclic Nucleotide Phosphodiesterases, Type 4
KW  - Cyclopropanes
KW  - Drug-Related Side Effects and Adverse Reactions
KW  - pathology
KW  - Female
KW  - Humans
KW  - Male
KW  - Maximum Tolerated Dose
KW  - Middle Aged
KW  - Neoplasms
KW  - drug therapy
KW  - Phosphatidylinositol 3-Kinases
KW  - genetics
KW  - Phosphodiesterase 4 Inhibitors
KW  - Phosphoinositide-3 Kinase Inhibitors
N1  - Publication Type: Clinical Trial, Phase I; Journal Article
UR  - https://doi.org/10.1158/1078-0432.CCR-16-1207
ER  -