TY - GEN AU - Furet,Pascal AU - Masuya,Keiichi AU - Kallen,Joerg AU - Stachyra-Valat,Thérèse AU - Ruetz,Stephan AU - Guagnano,Vito AU - Holzer,Philipp AU - Mah,Robert AU - Stutz,Stefan AU - Vaupel,Andrea AU - Chène,Patrick AU - Jeay,Sébastien AU - Schlapbach,Achim TI - Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument SN - 1464-3405 PY - 2017///0717 KW - Crystallography, X-Ray KW - Drug Discovery KW - Fluorescence Resonance Energy Transfer KW - Molecular Conformation KW - Proto-Oncogene Proteins c-mdm2 KW - antagonists & inhibitors KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2016.08.010 ER -