Furet, Pascal <br/><br/>
Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  10 2016 
 - 4837-4841 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2016.08.010  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Crystallography, X-Ray<br/>Drug Discovery<br/>Fluorescence Resonance Energy Transfer<br/>Molecular Conformation<br/>Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors<br/>Tumor Suppressor Protein p53--antagonists & inhibitors