Das, Sarita <br/><br/>
Quinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade.  [electronic resource] 

 -  Oncotarget  Jan 2017 
 - 248-267 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1949-2553 
<br/><br/><label>Standard No.: </label>10.18632/oncotarget.11335  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Caspase 3--metabolism<br/>Caspase 8--metabolism<br/>Caspase 9--metabolism<br/>Cell Line, Tumor<br/>Cytochromes c--metabolism<br/>Dose-Response Relationship, Drug<br/>Enzyme-Linked Immunosorbent Assay<br/>Fas-Associated Death Domain Protein--metabolism<br/>Female<br/>Gene Knockdown Techniques<br/>Humans<br/>Immunohistochemistry<br/>Mice<br/>Mice, Inbred BALB C<br/>Mitochondria--drug effects<br/>Molecular Dynamics Simulation<br/>Quinacrine--pharmacology<br/>RNA Interference<br/>RNA, Small Interfering--metabolism<br/>Reactive Oxygen Species--metabolism<br/>Receptors, TNF-Related Apoptosis-Inducing Ligand--agonists<br/>Signal Transduction--drug effects<br/>TNF-Related Apoptosis-Inducing Ligand--metabolism<br/>Xenograft Model Antitumor Assays