Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer. [electronic resource]
- The Journal of allergy and clinical immunology 12 2016
- 1712-1715 p. digital
Publication Type: Letter; Research Support, Non-U.S. Gov't
1097-6825
10.1016/j.jaci.2016.04.058 doi
Antibodies--immunology Aptamers, Nucleotide--immunology Clinical Trials, Phase III as Topic Humans Hypersensitivity, Immediate--immunology Multicenter Studies as Topic Polyethylene Glycols--adverse effects Randomized Controlled Trials as Topic