TY  - GEN
AU  - Druzhyna,Nadiya
AU  - Szczesny,Bartosz
AU  - Olah,Gabor
AU  - Módis,Katalin
AU  - Asimakopoulou,Antonia
AU  - Pavlidou,Athanasia
AU  - Szoleczky,Petra
AU  - Gerö,Domokos
AU  - Yanagi,Kazunori
AU  - Törö,Gabor
AU  - López-García,Isabel
AU  - Myrianthopoulos,Vassilios
AU  - Mikros,Emmanuel
AU  - Zatarain,John R
AU  - Chao,Celia
AU  - Papapetropoulos,Andreas
AU  - Hellmich,Mark R
AU  - Szabo,Csaba
TI  - Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer
SN  - 1096-1186
PY  - 2017///1220
KW  - Animals
KW  - Benserazide
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Colonic Neoplasms
KW  - drug therapy
KW  - Coumarins
KW  - Cystathionine beta-Synthase
KW  - antagonists & inhibitors
KW  - Drug Repositioning
KW  - methods
KW  - Energy Metabolism
KW  - Female
KW  - HCT116 Cells
KW  - HT29 Cells
KW  - Humans
KW  - Hydrazines
KW  - Hydrogen Sulfide
KW  - metabolism
KW  - Male
KW  - Mice
KW  - Mice, Nude
KW  - Mitochondria
KW  - Morpholines
KW  - Organothiophosphorus Compounds
KW  - Therapies, Investigational
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1016/j.phrs.2016.08.016
ER  -