Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) 09 2016
- 2250-60 p. digital
Publication Type: Journal Article
1550-6606
10.4049/jimmunol.1600492 doi
Adaptor Proteins, Signal Transducing--metabolism Animals Cell Proliferation Cell Survival Glycolysis--drug effects Mechanistic Target of Rapamycin Complex 1 Mice Multiprotein Complexes--genetics Phosphorylation--drug effects Precursor Cells, B-Lymphoid--drug effects Regulatory-Associated Protein of mTOR Signal Transduction Sirolimus--pharmacology TOR Serine-Threonine Kinases--deficiency Transcription Factors bcl-X Protein--genetics