TY  - GEN
AU  - Gstalder,Cécile
AU  - Ader,Isabelle
AU  - Cuvillier,Olivier
TI  - FTY720 (Fingolimod) Inhibits HIF1 and HIF2 Signaling, Promotes Vascular Remodeling, and Chemosensitizes in Renal Cell Carcinoma Animal Model
SN  - 1538-8514
PY  - 2017///0615
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Basic Helix-Loop-Helix Transcription Factors
KW  - genetics
KW  - Carcinoma, Renal Cell
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Disease Models, Animal
KW  - Drug Resistance, Neoplasm
KW  - Female
KW  - Fingolimod Hydrochloride
KW  - Gene Expression
KW  - Humans
KW  - Hypoxia
KW  - Hypoxia-Inducible Factor 1, alpha Subunit
KW  - Lysophospholipids
KW  - Mice
KW  - Neovascularization, Pathologic
KW  - Oxygen Consumption
KW  - Phosphotransferases (Alcohol Group Acceptor)
KW  - metabolism
KW  - Receptors, Lysosphingolipid
KW  - Signal Transduction
KW  - Sphingosine
KW  - analogs & derivatives
KW  - Vascular Endothelial Growth Factor A
KW  - biosynthesis
KW  - Vascular Remodeling
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1158/1535-7163.MCT-16-0167
ER  -