Mandalapu, Dhanaraju <br/><br/>
Synthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  09 2016 
 - 4223-32 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2016.07.053  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Apoptosis--drug effects<br/>Breast Neoplasms--metabolism<br/>Cell Cycle Checkpoints--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Click Chemistry<br/>Curcumin--chemistry<br/>Down-Regulation--drug effects<br/>Drug Screening Assays, Antitumor<br/>Female<br/>HEK293 Cells<br/>Half-Life<br/>Humans<br/>Male<br/>Membrane Potential, Mitochondrial--drug effects<br/>Proliferating Cell Nuclear Antigen--metabolism<br/>Prostatic Neoplasms--metabolism<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Triazoles--chemistry<br/>bcl-2-Associated X Protein--metabolism