TY - GEN AU - Christmann,Markus AU - Diesler,Kathrin AU - Majhen,Dragomira AU - Steigerwald,Christian AU - Berte,Nancy AU - Freund,Halima AU - Stojanović,Nikolina AU - Kaina,Bernd AU - Osmak,Maja AU - Ambriović-Ristov,Andreja AU - Tomicic,Maja T TI - Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair SN - 1949-2553 PY - 2018///0403 KW - Animals KW - Antineoplastic Agents, Alkylating KW - pharmacology KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - metabolism KW - Brain Neoplasms KW - drug therapy KW - Cell Line, Tumor KW - Cell Proliferation KW - DNA Breaks, Double-Stranded KW - Dacarbazine KW - analogs & derivatives KW - Down-Regulation KW - Drug Resistance, Neoplasm KW - genetics KW - Flow Cytometry KW - Gene Knockdown Techniques KW - Glioblastoma KW - Humans KW - Integrin alphaVbeta3 KW - antagonists & inhibitors KW - Integrin beta3 KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - NF-KappaB Inhibitor alpha KW - Neoplasm Grading KW - Peptides, Cyclic KW - Phosphorylation KW - Proto-Oncogene Proteins c-akt KW - RNA Interference KW - RNA, Small Interfering KW - Rad51 Recombinase KW - Receptor-Interacting Protein Serine-Threonine Kinases KW - Receptors, Vitronectin KW - Recombinational DNA Repair KW - Signal Transduction KW - Temozolomide KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.18632/oncotarget.10897 ER -