Zhang, Lei <br/><br/>
Aromatic heterocyclic esters of podophyllotoxin exert anti-MDR activity in human leukemia K562/ADR cells via ROS/MAPK signaling pathways.  [electronic resource] 

 -  European journal of medicinal chemistry  Nov 2016 
 - 226-235 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2016.07.050  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism<br/>Antineoplastic Agents--chemistry<br/>Cell Cycle Checkpoints--drug effects<br/>Drug Resistance, Multiple--drug effects<br/>Esters--chemistry<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Heterocyclic Compounds--chemistry<br/>Humans<br/>K562 Cells<br/>MAP Kinase Signaling System--drug effects<br/>Podophyllotoxin--chemistry<br/>Reactive Oxygen Species--metabolism<br/>Structure-Activity Relationship