TY - GEN AU - Lambert,Laura J AU - Challa,Anil K AU - Niu,Aidi AU - Zhou,Lihua AU - Tucholski,Janusz AU - Johnson,Maria S AU - Nagy,Tim R AU - Eberhardt,Alan W AU - Estep,Patrick N AU - Kesterson,Robert A AU - Grams,Jayleen M TI - Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology SN - 1754-8411 PY - 2017///1204 KW - Absorptiometry, Photon KW - Alleles KW - Amino Acid Sequence KW - Animals KW - Base Sequence KW - Biomechanical Phenomena KW - Body Composition KW - CRISPR-Cas Systems KW - genetics KW - Cancellous Bone KW - diagnostic imaging KW - Femur KW - Founder Effect KW - Genetic Techniques KW - Glucose Tolerance Test KW - INDEL Mutation KW - Insulin KW - metabolism KW - Male KW - Models, Animal KW - Osteocalcin KW - chemistry KW - Rats KW - Species Specificity KW - X-Ray Microtomography N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural UR - https://doi.org/10.1242/dmm.025247 ER -