Wood, Michael R <br/><br/>
Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  09 2016 
 - 4282-6 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2016.07.042  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation<br/>Animals<br/>Central Nervous System--metabolism<br/>Drug Discovery<br/>Humans<br/>Ketones--chemical synthesis<br/>Molecular Structure<br/>Receptor, Muscarinic M1--agonists<br/>Structure-Activity Relationship