TY  - GEN
AU  - Cheng,Wei-Chieh
AU  - Wang,Jen-Hon
AU  - Li,Huang-Yi
AU  - Lu,Sheng-Jhih
AU  - Hu,Jia-Ming
AU  - Yun,Wen-Yi
AU  - Chiu,Cheng-Hsin
AU  - Yang,Wen-Bin
AU  - Chien,Yin-Hsiu
AU  - Hwu,Wuh-Liang
TI  - Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency
SN  - 1768-3254
PY  - 2017///0217
KW  - Cell Line, Tumor
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - Enzyme Replacement Therapy
KW  - methods
KW  - Enzyme Stability
KW  - drug effects
KW  - Fabry Disease
KW  - drug therapy
KW  - Humans
KW  - Imino Pyranoses
KW  - Imino Sugars
KW  - chemical synthesis
KW  - Mannitol
KW  - analogs & derivatives
KW  - Pyrrolidines
KW  - Small Molecule Libraries
KW  - Stereoisomerism
KW  - alpha-Galactosidase
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.ejmech.2016.07.025
ER  -