TY  - GEN
AU  - Wang,Haixia
AU  - Lawson,J David
AU  - Scorah,Nick
AU  - Kamran,Ruhi
AU  - Hixon,Mark S
AU  - Atienza,Joy
AU  - Dougan,Douglas R
AU  - Sabat,Mark
TI  - Design, synthesis and optimization of novel Alk5 (activin-like kinase 5) inhibitors
SN  - 1464-3405
PY  - 2017///0829
KW  - Animals
KW  - Cyclization
KW  - Drug Design
KW  - Enzyme Activation
KW  - drug effects
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Humans
KW  - Indoles
KW  - Inhibitory Concentration 50
KW  - Molecular Structure
KW  - Protein Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Pyrimidines
KW  - chemistry
KW  - Pyrroles
KW  - Rats
KW  - Receptor, Transforming Growth Factor-beta Type I
KW  - Receptors, Transforming Growth Factor beta
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2016.07.030
ER  -