Wang, Haixia <br/><br/>
Design, synthesis and optimization of novel Alk5 (activin-like kinase 5) inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  09 2016 
 - 4334-9 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2016.07.030  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cyclization<br/>Drug Design<br/>Enzyme Activation--drug effects<br/>Enzyme Inhibitors--chemical synthesis<br/>Humans<br/>Indoles--chemical synthesis<br/>Inhibitory Concentration 50<br/>Molecular Structure<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Pyrimidines--chemistry<br/>Pyrroles--chemistry<br/>Rats<br/>Receptor, Transforming Growth Factor-beta Type I<br/>Receptors, Transforming Growth Factor beta--antagonists & inhibitors