TY - GEN AU - Mert,Samet AU - Alım,Zuhal AU - İşgör,Mehmet Mustafa AU - Beydemir,Şükrü AU - Kasımoğulları,Rahmi TI - The synthesis of novel pyrazole-3,4-dicarboxamides bearing 5-amino-1,3,4-thiadiazole-2-sulfonamide moiety with effective inhibitory activity against the isoforms of human cytosolic carbonic anhydrase I and II SN - 1090-2120 PY - 2017///0629 KW - Carbonic Anhydrase I KW - antagonists & inhibitors KW - Carbonic Anhydrase II KW - Carbonic Anhydrase Inhibitors KW - chemical synthesis KW - Cytosol KW - drug effects KW - Dose-Response Relationship, Drug KW - Humans KW - Isoenzymes KW - Molecular Structure KW - Pyrazoles KW - Structure-Activity Relationship KW - Sulfonamides KW - chemistry KW - Thiadiazoles N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bioorg.2016.07.006 ER -