TY - GEN AU - Ray Chaudhuri,Arnab AU - Callen,Elsa AU - Ding,Xia AU - Gogola,Ewa AU - Duarte,Alexandra A AU - Lee,Ji-Eun AU - Wong,Nancy AU - Lafarga,Vanessa AU - Calvo,Jennifer A AU - Panzarino,Nicholas J AU - John,Sam AU - Day,Amanda AU - Crespo,Anna Vidal AU - Shen,Binghui AU - Starnes,Linda M AU - de Ruiter,Julian R AU - Daniel,Jeremy A AU - Konstantinopoulos,Panagiotis A AU - Cortez,David AU - Cantor,Sharon B AU - Fernandez-Capetillo,Oscar AU - Ge,Kai AU - Jonkers,Jos AU - Rottenberg,Sven AU - Sharan,Shyam K AU - Nussenzweig,André TI - Replication fork stability confers chemoresistance in BRCA-deficient cells SN - 1476-4687 PY - 2016///0824 KW - Animals KW - Carrier Proteins KW - genetics KW - Cell Line, Tumor KW - Cisplatin KW - pharmacology KW - DNA KW - biosynthesis KW - DNA Breaks, Double-Stranded KW - DNA Damage KW - drug effects KW - DNA Helicases KW - DNA Repair KW - DNA Repair Enzymes KW - antagonists & inhibitors KW - DNA Replication KW - DNA-Binding Proteins KW - Drug Resistance, Neoplasm KW - Embryonic Stem Cells KW - Female KW - Gene Deletion KW - Genes, BRCA1 KW - Genes, BRCA2 KW - Homologous Recombination KW - MRE11 Homologue Protein KW - Mice KW - Neoplasms KW - Nuclear Proteins KW - deficiency KW - Poly (ADP-Ribose) Polymerase-1 KW - Poly(ADP-ribose) Polymerase Inhibitors KW - Poly(ADP-ribose) Polymerases N1 - Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/nature18325 ER -