Donato, E
Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors. [electronic resource]
- Leukemia 02 2017
- 479-490 p. digital
Publication Type: Journal Article
ISSN: 1476-5551
Standard No.: 10.1038/leu.2016.182 doi
Subjects--Topical Terms: Azepines--pharmacology Cell Cycle--drug effects Cell Cycle Proteins Cell Line, Tumor Cell Proliferation--drug effects Chromatin--genetics Cyclin-Dependent Kinase 9--metabolism E2F Transcription Factors--metabolism Enhancer Elements, Genetic Gene Expression Regulation, Neoplastic--drug effects Humans Neoplasms--genetics Nuclear Proteins--metabolism Promoter Regions, Genetic Protein Binding Protein Kinase Inhibitors--pharmacology Proto-Oncogene Proteins c-myc--genetics RNA Polymerase II--metabolism Transcription Factors--metabolism Transcription, Genetic Triazoles--pharmacology