DiMauro, Erin F <br/><br/>
Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors.  [electronic resource] 

 -  Journal of medicinal chemistry  09 2016 
 - 7818-39 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.6b00425  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Benzamides--chemical synthesis<br/>Cell Line<br/>Female<br/>Histamine<br/>Humans<br/>Male<br/>Mice, Inbred C57BL<br/>Microsomes, Liver--metabolism<br/>Molecular Docking Simulation<br/>NAV1.7 Voltage-Gated Sodium Channel--metabolism<br/>Pruritus--chemically induced<br/>Radioligand Assay<br/>Rats<br/>Structure-Activity Relationship<br/>Sulfonamides--chemical synthesis<br/>Voltage-Gated Sodium Channel Blockers--chemical synthesis