TY  - GEN
AU  - Murone,Maximilien
AU  - Vaslin Chessex,Anne
AU  - Attinger,Antoine
AU  - Ramachandra,Raghuveer
AU  - Shetty,Shankar J
AU  - Daginakatte,Girish
AU  - Sengupta,Saumitra
AU  - Marappan,Sivapriya
AU  - Dhodheri,Samiulla
AU  - Rigotti,Stefania
AU  - Bachhav,Yogeshwar
AU  - Brienza,Silvano
AU  - Traxler,Peter
AU  - Lang,Marc
AU  - Aguet,Michel
AU  - Zoete,Vincent
AU  - Michielin,Olivier
AU  - Nicholas,Courtney
AU  - Johnson,Faye M
AU  - Ramachandra,Murali
AU  - McAllister,Andres
TI  - Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases
SN  - 1538-8514
PY  - 2017///0615
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Apoptosis
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Disease Models, Animal
KW  - Drug Design
KW  - Humans
KW  - Janus Kinases
KW  - antagonists & inhibitors
KW  - Mice
KW  - Molecular Conformation
KW  - Molecular Docking Simulation
KW  - Molecular Dynamics Simulation
KW  - Neoplasm Metastasis
KW  - Neoplasms
KW  - drug therapy
KW  - Protein Kinase Inhibitors
KW  - Receptor Protein-Tyrosine Kinases
KW  - STAT3 Transcription Factor
KW  - metabolism
KW  - Signal Transduction
KW  - Tumor Burden
KW  - Xenograft Model Antitumor Assays
KW  - src-Family Kinases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/1535-7163.MCT-15-0974
ER  -