Murone, Maximilien <br/><br/>
Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases.  [electronic resource] 

 -  Molecular cancer therapeutics  10 2016 
 - 2334-2343 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-8514 
<br/><br/><label>Standard No.: </label>10.1158/1535-7163.MCT-15-0974  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemistry<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Disease Models, Animal<br/>Drug Design<br/>Humans<br/>Janus Kinases--antagonists & inhibitors<br/>Mice<br/>Molecular Conformation<br/>Molecular Docking Simulation<br/>Molecular Dynamics Simulation<br/>Neoplasm Metastasis<br/>Neoplasms--drug therapy<br/>Protein Kinase Inhibitors--chemistry<br/>Receptor Protein-Tyrosine Kinases--antagonists & inhibitors<br/>STAT3 Transcription Factor--metabolism<br/>Signal Transduction--drug effects<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays<br/>src-Family Kinases--antagonists & inhibitors