TY - GEN AU - Martínez-Hoyos,María AU - Perez-Herran,Esther AU - Gulten,Gulcin AU - Encinas,Lourdes AU - Álvarez-Gómez,Daniel AU - Alvarez,Emilio AU - Ferrer-Bazaga,Santiago AU - García-Pérez,Adolfo AU - Ortega,Fátima AU - Angulo-Barturen,Iñigo AU - Rullas-Trincado,Joaquin AU - Blanco Ruano,Delia AU - Torres,Pedro AU - Castañeda,Pablo AU - Huss,Sophie AU - Fernández Menéndez,Raquel AU - González Del Valle,Silvia AU - Ballell,Lluis AU - Barros,David AU - Modha,Sundip AU - Dhar,Neeraj AU - Signorino-Gelo,François AU - McKinney,John D AU - García-Bustos,Jose Francisco AU - Lavandera,Jose Luis AU - Sacchettini,James C AU - Jimenez,M Soledad AU - Martín-Casabona,Nuria AU - Castro-Pichel,Julia AU - Mendoza-Losana,Alfonso TI - Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor SN - 2352-3964 PY - 2017///0214 KW - Animals KW - Antitubercular Agents KW - chemistry KW - Binding Sites KW - Catalytic Domain KW - Disease Models, Animal KW - Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) KW - antagonists & inhibitors KW - Enzyme Inhibitors KW - Female KW - Humans KW - Mice KW - Microbial Sensitivity Tests KW - Microsomes KW - Models, Molecular KW - Mutation KW - Mycobacterium tuberculosis KW - drug effects KW - Protein Binding KW - Protein Conformation KW - Tuberculosis KW - drug therapy KW - Tuberculosis, Multidrug-Resistant N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ebiom.2016.05.006 ER -