Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. II- Identification of sub-units for the characterization of even and odd load drug species. [electronic resource]
- Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Oct 2016
- 91-102 p. digital
Publication Type: Journal Article
1873-376X
10.1016/j.jchromb.2016.06.049 doi
Brentuximab Vedotin Chromatography, Reverse-Phase--methods Cysteine--analysis Hydrophobic and Hydrophilic Interactions Immunoconjugates--chemistry Isomerism Mass Spectrometry--methods