TY - GEN AU - Stavrinides,Anna AU - Tatsis,Evangelos C AU - Caputi,Lorenzo AU - Foureau,Emilien AU - Stevenson,Clare E M AU - Lawson,David M AU - Courdavault,Vincent AU - O'Connor,Sarah E TI - Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity SN - 2041-1723 PY - 2018///0911 KW - Catalytic Domain KW - Catharanthus KW - genetics KW - Cell Nucleus KW - metabolism KW - Cloning, Molecular KW - Gene Expression Regulation, Plant KW - Models, Molecular KW - Molecular Docking Simulation KW - Mutagenesis, Site-Directed KW - Plant Proteins KW - chemistry KW - Protein Conformation KW - Secologanin Tryptamine Alkaloids KW - Stereoisomerism KW - Vinca Alkaloids N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ncomms12116 ER -