TY - GEN AU - Kumari,Manju AU - Wang,Xun AU - Lantier,Louise AU - Lyubetskaya,Anna AU - Eguchi,Jun AU - Kang,Sona AU - Tenen,Danielle AU - Roh,Hyun Cheol AU - Kong,Xingxing AU - Kazak,Lawrence AU - Ahmad,Rasheed AU - Rosen,Evan D TI - IRF3 promotes adipose inflammation and insulin resistance and represses browning SN - 1558-8238 PY - 2017///0926 KW - 3T3-L1 Cells KW - Adipocytes KW - cytology KW - Adipose Tissue KW - immunology KW - Adiposity KW - Adult KW - Animals KW - Blood Glucose KW - metabolism KW - Diet KW - Female KW - Gene Expression Regulation KW - Glucose Clamp Technique KW - Glucose Transporter Type 4 KW - genetics KW - HEK293 Cells KW - Homeostasis KW - Humans KW - Inflammation KW - Insulin Resistance KW - Interferon Regulatory Factor-3 KW - Male KW - Mice KW - Mice, Transgenic KW - Middle Aged KW - NF-kappa B KW - Obesity KW - Toll-Like Receptor 3 KW - Toll-Like Receptor 4 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural UR - https://doi.org/10.1172/JCI86080 ER -