Patnaik, Amita <br/><br/>
Phase 1 study to evaluate the effect of the MEK inhibitor trametinib on cardiac repolarization in patients with solid tumours.  [electronic resource] 

 -  Cancer chemotherapy and pharmacology  Sep 2016 
 - 491-500 p.  digital 
<br/><br/> Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study 
<br/><br/><label>ISSN: </label>1432-0843 
<br/><br/><label>Standard No.: </label>10.1007/s00280-016-3090-y  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adolescent<br/>Adult<br/>Aged<br/>Antineoplastic Agents--administration & dosage<br/>Area Under Curve<br/>Cardiotoxicity--epidemiology<br/>Electrocardiography<br/>Electrocardiography, Ambulatory<br/>Female<br/>Humans<br/>MAP Kinase Kinase 1--antagonists & inhibitors<br/>MAP Kinase Kinase 2--antagonists & inhibitors<br/>Male<br/>Middle Aged<br/>Models, Biological<br/>Neoplasms--drug therapy<br/>Protein Kinase Inhibitors--administration & dosage<br/>Pyridones--administration & dosage<br/>Pyrimidinones--administration & dosage<br/>Single-Blind Method<br/>Young Adult