Next-generation sequencing with a myeloid gene panel in core-binding factor AML showed KIT activation loop and TET2 mutations predictive of outcome. [electronic resource]
- Blood cancer journal 07 2016
- e442 p. digital
Publication Type: Journal Article
2044-5385
10.1038/bcj.2016.51 doi
Adolescent Adult Antineoplastic Combined Chemotherapy Protocols--therapeutic use Combined Modality Therapy Core Binding Factors--genetics DNA Methylation DNA Mutational Analysis DNA-Binding Proteins--genetics Dioxygenases Female Hematopoietic Stem Cell Transplantation--methods High-Throughput Nucleotide Sequencing Humans Leukemia, Myeloid, Acute--genetics Male Middle Aged Mutation Prognosis Proto-Oncogene Proteins--genetics Proto-Oncogene Proteins c-kit--genetics Signal Transduction Survival Analysis Translocation, Genetic Transplantation, Homologous Young Adult