TY - GEN AU - Berenguer-Daizé,Caroline AU - Astorgues-Xerri,Lucile AU - Odore,Elodie AU - Cayol,Mylène AU - Cvitkovic,Esteban AU - Noel,Kay AU - Bekradda,Mohamed AU - MacKenzie,Sarah AU - Rezai,Keyvan AU - Lokiec,François AU - Riveiro,Maria E AU - Ouafik,L'Houcine TI - OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models SN - 1097-0215 PY - 2017///0501 KW - Acetanilides KW - administration & dosage KW - Animals KW - Antineoplastic Agents KW - Antineoplastic Combined Chemotherapy Protocols KW - Blood-Brain Barrier KW - drug effects KW - Brain Neoplasms KW - drug therapy KW - Camptothecin KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Survival KW - Dacarbazine KW - Drug Synergism KW - Everolimus KW - Gene Expression Regulation, Neoplastic KW - Glioblastoma KW - Heterocyclic Compounds, 3-Ring KW - Humans KW - Irinotecan KW - Mice KW - Temozolomide KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/ijc.30256 ER -