TY - GEN AU - Ferrándiz,María-José AU - Martín-Galiano,Antonio J AU - Arnanz,Cristina AU - Camacho-Soguero,Isabel AU - Tirado-Vélez,José-Manuel AU - de la Campa,Adela G TI - An increase in negative supercoiling in bacteria reveals topology-reacting gene clusters and a homeostatic response mediated by the DNA topoisomerase I gene SN - 1362-4962 PY - 2017///0613 KW - Benzodioxoles KW - pharmacology KW - DNA Gyrase KW - genetics KW - DNA Topoisomerases, Type I KW - biosynthesis KW - DNA, Bacterial KW - drug effects KW - DNA, Superhelical KW - Gene Expression Regulation, Bacterial KW - Genes, Bacterial KW - Homeostasis KW - Microbial Viability KW - Multigene Family KW - Phenanthrenes KW - Streptococcus pneumoniae KW - Transcription, Genetic KW - Transcriptome N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/nar/gkw602 ER -