Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice. [electronic resource]
- American journal of respiratory cell and molecular biology 11 2016
- 722-735 p. digital
Publication Type: Journal Article
1535-4989
10.1165/rcmb.2015-0349OC doi
Acute Lung Injury--etiology Adaptor Proteins, Signal Transducing--metabolism Alveolar Epithelial Cells--metabolism Animals Animals, Newborn Apoptosis--drug effects Autophagy--drug effects Bronchopulmonary Dysplasia--complications Cell Line Female Humans Hyperoxia--complications Hypertension, Pulmonary--complications Hypertrophy, Right Ventricular--complications Infant, Newborn Lung--metabolism Mice Microtubule-Associated Proteins--metabolism Naphthyridines--pharmacology Phenotype Regulatory-Associated Protein of mTOR Time Factors Tumor Suppressor Protein p53--metabolism