Pisani, Leonardo <br/><br/>
Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents.  [electronic resource] 

 -  Journal of medicinal chemistry  07 2016 
 - 6791-806 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.6b00562  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcholinesterase--metabolism<br/>Animals<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Cholinesterase Inhibitors--chemical synthesis<br/>Coumarins--chemical synthesis<br/>Dogs<br/>Dose-Response Relationship, Drug<br/>Humans<br/>Madin Darby Canine Kidney Cells<br/>Molecular Structure<br/>Monoamine Oxidase--metabolism<br/>Monoamine Oxidase Inhibitors--chemical synthesis<br/>Neuroprotective Agents--chemical synthesis<br/>Oxidative Stress--drug effects<br/>Solubility<br/>Structure-Activity Relationship<br/>Water--chemistry