Hou, Wen <br/><br/>
Novel securinine derivatives as topoisomerase I based antitumor agents.  [electronic resource] 

 -  European journal of medicinal chemistry  Oct 2016 
 - 149-163 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2016.06.021  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemistry<br/>Azepines--chemistry<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>DNA Cleavage--drug effects<br/>DNA Topoisomerases, Type I--chemistry<br/>Drug Design<br/>Heterocyclic Compounds, Bridged-Ring--chemistry<br/>Humans<br/>Lactones--chemistry<br/>Models, Molecular<br/>Piperidines--chemistry<br/>Protein Conformation<br/>Structure-Activity Relationship<br/>Topoisomerase I Inhibitors--chemistry