TY - GEN AU - Temple,Kayla J AU - Wright,Elia N AU - Fierke,Carol A AU - Gibbs,Richard A TI - Exploration of GGTase-I substrate requirements. Part 1: Synthesis and biochemical evaluation of novel aryl-modified geranylgeranyl diphosphate analogs SN - 1464-3405 PY - 2017///0718 KW - Alkyl and Aryl Transferases KW - antagonists & inhibitors KW - Animals KW - Dose-Response Relationship, Drug KW - Enzyme Inhibitors KW - chemical synthesis KW - Humans KW - Molecular Structure KW - Polyisoprenyl Phosphates KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.bmcl.2016.06.034 ER -