Genetic and clinical biomarkers of tocilizumab response in patients with rheumatoid arthritis. [electronic resource]
- Pharmacological research 09 2016
- 264-271 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1096-1186
10.1016/j.phrs.2016.06.016 doi
Adolescent Adult Aged Aged, 80 and over Antibodies, Monoclonal, Humanized--adverse effects Antigens, CD--genetics Antigens, Differentiation, T-Lymphocyte--genetics Antirheumatic Agents--adverse effects Arthritis, Rheumatoid--blood Chi-Square Distribution Female Gene Frequency Genome-Wide Association Study Heterozygote Homozygote Humans Lectins, C-Type--genetics Linear Models Logistic Models Male Middle Aged Multivariate Analysis N-Acetylgalactosaminyltransferases--genetics Odds Ratio Pharmacogenetics Pharmacogenomic Testing Pharmacogenomic Variants Phenotype Predictive Value of Tests Recovery of Function Remission Induction Retrospective Studies Risk Factors Treatment Outcome Young Adult Polypeptide N-acetylgalactosaminyltransferase