TY - GEN AU - Doumith,M AU - Mushtaq,S AU - Livermore,D M AU - Woodford,N TI - New insights into the regulatory pathways associated with the activation of the stringent response in bacterial resistance to the PBP2-targeted antibiotics, mecillinam and OP0595/RG6080 SN - 1460-2091 PY - 2017///0808 KW - Amdinocillin KW - metabolism KW - Anti-Bacterial Agents KW - pharmacology KW - Azabicyclo Compounds KW - Bacterial Proteins KW - genetics KW - Drug Resistance, Multiple, Bacterial KW - Escherichia coli KW - cytology KW - Escherichia coli Proteins KW - antagonists & inhibitors KW - Gene Expression Regulation, Bacterial KW - Genetic Variation KW - Genome, Bacterial KW - High-Throughput Nucleotide Sequencing KW - Lactams KW - Microscopy, Electron, Transmission KW - Mutation KW - Penicillin-Binding Proteins KW - Sigma Factor KW - beta-Lactamase Inhibitors N1 - Publication Type: Journal Article UR - https://doi.org/10.1093/jac/dkw230 ER -