TY - GEN AU - Hing,Z A AU - Fung,H Y J AU - Ranganathan,P AU - Mitchell,S AU - El-Gamal,D AU - Woyach,J A AU - Williams,K AU - Goettl,V M AU - Smith,J AU - Yu,X AU - Meng,X AU - Sun,Q AU - Cagatay,T AU - Lehman,A M AU - Lucas,D M AU - Baloglu,E AU - Shacham,S AU - Kauffman,M G AU - Byrd,J C AU - Chook,Y M AU - Garzon,R AU - Lapalombella,R TI - Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies SN - 1476-5551 PY - 2017///0814 KW - Animals KW - Antineoplastic Agents KW - therapeutic use KW - Hematologic Neoplasms KW - drug therapy KW - Heterografts KW - Humans KW - Karyopherins KW - antagonists & inhibitors KW - Mice KW - Neoplasm Invasiveness KW - Receptors, Cytoplasmic and Nuclear KW - Survival Rate KW - Treatment Outcome KW - Exportin 1 Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/leu.2016.136 ER -