TY  - GEN
AU  - Kimura,Masafumi
AU  - Eisenach,James C
AU  - Hayashida,Ken-Ichiro
TI  - Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus
SN  - 1872-6623
PY  - 2017///0306
KW  - Amines
KW  - therapeutic use
KW  - Analgesics
KW  - Animals
KW  - Antihypertensive Agents
KW  - pharmacology
KW  - Atropine
KW  - Bronchodilator Agents
KW  - CREB-Binding Protein
KW  - metabolism
KW  - Clonidine
KW  - Cyclohexanecarboxylic Acids
KW  - Disease Models, Animal
KW  - Excitatory Amino Acid Transporter 2
KW  - genetics
KW  - Gabapentin
KW  - Locus Coeruleus
KW  - drug effects
KW  - Male
KW  - Norepinephrine
KW  - Pain Threshold
KW  - Peripheral Nerve Injuries
KW  - drug therapy
KW  - RNA, Small Interfering
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Spinal Cord Dorsal Horn
KW  - Time Factors
KW  - gamma-Aminobutyric Acid
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1097/j.pain.0000000000000608
ER  -